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Endocrine Abstracts

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ea0063p873 | Adrenal and Neuroendocrine Tumours 3 | ECE2019

Immunohistochemical expression of ephrines A2 and A4 receptors in neuroendocrine neoplasms: preliminary results

Alexandraki Krystallenia , Antonopoulou Ioanna , Karaflou Maria , Christakou Charikleia , Mavroeidi Vasiliki , Karapanagioti Aggeliki , Lekkakou Maria , Anagnostou Elli , Tsoli Marina , Angelousi Anna , Delladetsima Ioanna Kassiani , Felekouras Evangelos , Sotiropoulos Georgios , Kaltsas Gregory , Theocharis Stamatios

Introduction: Ephrin receptors (EPHs) have a role in tumor growth, invasion, angiogenesis and metastasis of several neoplasms. Aim of the study was to investigate the expression and possible clinical significance of EPH-A4 and EPH-A2 protein expression in the pathophysiology of neuroendocrine neoplasms (NENs).Methods: EPH-A4 and -A2 protein expression was assessed by immunohistochemical analysis along with Ki-67 proliferation index (%) on 28 paraffin emb...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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